Biology has increasingly turned into a data-rich science. Since the first biological sequence database was created in 1960’s, the need for storing and communicating large datasets has grown tremendously. To cope with these needs, a lot of databases had been created. Most of them vanished in a few years; some of them got strong financial support from governments and became dominant in biological research, while others might be commercialized and be used in special fields.

BIND (the Biomolecular Interaction Network Database) was a web-based system，archives biomolecular interaction, complex and pathway information. It was developed by a team led by C.W. Hogue from University of Toronto, published by 2001, and was connected with Genbank. From 2003, the new government of Canada became less interested in supporting public databases like BIND, ergo left it with a series of financial problems. Prof. Hogue managed to run it until 2005 by seeking collaborations with the government of Singapore and made the database well known in the field. After 2005, the Singapore government also gave up on supporting BIND led the database suspended updating. The Fates of similar databases need further observation. But it was widely understood to manage a massive database like BIND requires strong finance support and high level human resources. This paper reviewed the development of BIND and discussed how the intellectual property, the national policies and international collaborations affected its funding resources. It raises questions rather than answers, and hopefully might draw more public attention on the funding issue of biological databases.