Dunhuang was a Chinese town since Han times. It was briefly ruled by Tibetans (781-848) and subsequently controlled again by Chinese. It is within this context that we find various aspects of Sino-Tibetan culture in Dunhuang. These connections and exchanges, which have been studied in areas such as art, religion and history, are also important in medical interactions. This paper is based on an analysis of the Tibetan medical manuscripts from Dunhuang and will focus on the Tibetan moxibustion manuscripts. The paper will discuss some of the similarities and differences between the Tibetan moxibustion manuscripts from Dunhuang and the Chinese moxibustion texts from Dunhuang. This discussion will raise the following question: What can these texts teach us about exchanges between Tibetan and Chinese medical ideas?